Avicenna’s definition of medicine in his Canon established a foundational epistemological framework that also provoked a vibrant critical commentary tradition, predominantly centered in the Persian intellectual sphere. While this critical current is well-studied, the response it elicited remains underexplored. This article introduces and analyzes a previously unstudied anonymous Arabic treatise, dedicated to the Ottoman Sultan Bayezid II (r. 1481–1512), which offers a sophisticated philosophical defense of Avicenna’s definition. Through a close textual analysis, this study deconstructs the author’s meticulous arguments. The defense reaffirms medicine’s status as a ‘science’ (ʿilm) by defining it as encompassing both certain (yaqīnī) and conjectural (ẓannī) knowledge; it establishes Avicenna’s formulation as superior to al-Fārābī’s by highlighting its inclusion of preventative medicine; and it demonstrates the definition’s structural coherence by aligning it with the four Aristotelian causes. The study concludes that this treatise is vital evidence of a dynamic, cross-regional intellectual dialogue. As a direct response to the Eastern critical tradition, the work exemplifies the ‘entangled histories’ of Iran and Türkiye, revealing an integrated scholarly landscape where a shared Avicennan heritage was actively debated, contested, and defended across cultural and political boundaries.
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Ṣafī, M., 1700. Risālah fī taʿrīf al-Ṭibb (Treatise on the Definition of Medicine). [Manuscript] Dublin, Ireland: Chester Beatty Library.
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The 2nd History of Medicine Meeting: Entangled Histories: Contribution of Iran and Türkiye to the Development of Medical Sciences; 2025 Oct 7-10; Shiraz, Iran
Arezaei, H. and Mirzadeh Vaghefi, M. S. (2025). The Architecture of Medical Knowledge: An Analysis of a Post-Avicennan Commentary on Avicenna’s Definition of Medicine. Journal of Research on History of Medicine, 14(Suppl. 1), 11-14. doi: 10.30476/rhm.2025.108995.1379
MLA
Arezaei, H. , and Mirzadeh Vaghefi, M. S. . "The Architecture of Medical Knowledge: An Analysis of a Post-Avicennan Commentary on Avicenna’s Definition of Medicine", Journal of Research on History of Medicine, 14, Suppl. 1, 2025, 11-14. doi: 10.30476/rhm.2025.108995.1379
HARVARD
Arezaei, H., Mirzadeh Vaghefi, M. S. (2025). 'The Architecture of Medical Knowledge: An Analysis of a Post-Avicennan Commentary on Avicenna’s Definition of Medicine', Journal of Research on History of Medicine, 14(Suppl. 1), pp. 11-14. doi: 10.30476/rhm.2025.108995.1379
CHICAGO
H. Arezaei and M. S. Mirzadeh Vaghefi, "The Architecture of Medical Knowledge: An Analysis of a Post-Avicennan Commentary on Avicenna’s Definition of Medicine," Journal of Research on History of Medicine, 14 Suppl. 1 (2025): 11-14, doi: 10.30476/rhm.2025.108995.1379
VANCOUVER
Arezaei, H., Mirzadeh Vaghefi, M. S. The Architecture of Medical Knowledge: An Analysis of a Post-Avicennan Commentary on Avicenna’s Definition of Medicine. Journal of Research on History of Medicine, 2025; 14(Suppl. 1): 11-14. doi: 10.30476/rhm.2025.108995.1379